Figure 8
From: Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat
Mature CD4 or CD8 positive T lymphocytes in the peripheral blood of Rag1 mutant rats . A Absence of CD4+/CD8+ lymphocytes in wild type and Rag1 mutant rats. B and C Reduction of CD4+/CD3+ and CD8+/CD3+ T cells. D and E While there are no differences in the population of CD25+/CD4+ T cells the number of CD25+/CD8+ lymphocytes was reduced. orange: autofluorescent cells; green: FITC positive lymphocytes; blue: PE positive lymphocytes.