Table 2 Effect of LPS + PHA stimulation on the release of cytokines (Release of IL-1β, TNF-α, IL-6, IL-10 and IFN-γ in whole blood from wild type subjects (P2X7WT) and subjects homozygous for the Glu496Ala polymorphism (P2X7MUT) ^a) )

IL-1β

2.2 ± 0.16

2.6 ± 0.35

5,644 ± 3,261

3,440 ± 1,647

0.529

TNF-α

6.6 ± 1.04

7.1 ± 0.33

7,784 ± 3,470

5,173 ± 1,380

0.504

IL-6

2.5 ± 0.21

2.5 ± 0.35

13,922 ± 5,790

19,804 ± 8,003

0.064

IL-10

2.4 ± 0.21

2.0 ± 0.10

291 ± 104

305 ± 167

0.968

IFN-γ

15.4 ± 3.93

13.4 ± 6.38

701 ± 283

791 ± 144

0.766