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Figure 2 | BMC Immunology

Figure 2

From: The major CD8 T cell effector memory subset in the normal and Chlamydia trachomatis-infected human endocervix is low in perforin

Figure 2

Immunohistochemical staining profile of a representative C. trachomatis -positive tissue sample. (A) CD8, perforin and isotype-control staining pattern of serial sections of a representative paraffin-embedded endocervical tissue from the C. trachomatis-infected population (n=4), (B) Sections of a cell pellet consisting of peripheral blood mononuclear cells (PBMCs) cushioned with HeLa 229 cervical epithelial cells is shown as positive staining control. Sections stained with isotype control antibodies were used as negative control. Vulcan fast red stain indicates CD8 or perforin positive cells. All tissue and cell pellet sections were counterstained with hematoxylin. The majority of CD8 T cells that infiltrate the C. trachomatis-infected tissues do not express detectable levels of perforin.

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BMC Immunology

ISSN: 1471-2172

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