Identification and characterization of H-2d restricted CD4+ T cell epitopes on Lpp20 of Helicobacter pylori

BMC Immunology

Table 1 Prediction and synthesis of potential CD4 ⁺ T cell epitopes on Lpp20

Name	Residues	Sequence	MHC restriction	Scores	Theoretical Mr	Actual Mr	Purity (100%)
L1	83 ~ 97aa	N QAT AK ARANLAANL	I⇀A^d	32	1526.72	1526.7	93.5
L2	58 ~ 72aa	Y EKY SG VFLGRAEDL	I⇀A^d	30	1746.94	1746.9	93.0
L3	12 ~ 26aa	S VIA AM VIVGCSHAP	I⇀A^d	29	1454.77	1454.8	86.3
L4	8 ~ 22aa	I LGM SV IAAMVIVGC	I⇀A^d	26	1476.91	1476.9	Crude
	7 ~ 21aa	K ILG MS VIAAMVIVG	I⇀A^d	24
L5	135 ~ 149aa	K ELI AS KML ARYVGK	I⇀E^d	22	1707.11	1707.1	95.6
L6	44 ~ 58aa	A PDVV GDL EKVAKY	I⇀E^d	20	1689.93	1689.9	91.4
	58 ~ 72aa	Y EKY SG VFL GRAEDL	I⇀E^d	20
L7	150 ~ 164aa	D RVF VL VGL DKQIVD	I⇀E^d	20	1716.01	1716.0	90.7
L8	77 ~ 92aa	D VDY ST NQA TAKARA	I⇀E^d	18	1610.78	1610.7	91.8

ISSN: 1471-2172