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Figure 1 | BMC Immunology

Figure 1

From: Cervical cancer cell lines expressing NKG2D-ligands are able to down-modulate the NKG2D receptor on NKL cells with functional implications

Figure 1

Expression pattern of ULBP1-4 in different cervical cancer cell lines. MFI of the different ULBP proteins in cervical cancer cell lines and non-tumorigenic HaCaT keratinocytes was measured by flow cytometry using a mouse anti-ULBP1, ULBP2, ULBP3, and ULBP4 primary antibodies followed by incubation with PE-conjugated anti-mouse secondary antibody (A). Representative flow cytometry histograms for each cell line are shown in (B). While ULBP1 is practically absent in all cell lines, ULBP2 is expressed universally, with cell surface staining especially high in SiHa and HeLa cells. ULBP3 expression is moderate in HaCaT, C33A, and HeLa cells, but absent in SiHa cells. ULBP4 expression is seen solely in the non-tumorigenic HaCaT keratinocytes..

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