Figure 8

Enhanced BAF250 recruitment to IL-10 locus in stimulated Th2 cells in the absence of BAF180 Binding of BRG1, BAF180 and BAF250 was detected by ChIP-PCR at the indicated sites in the IL-10 locus. Signal is expressed as percent of the input chromatin. Control IP levels are less than 0.05% input. Nfm is a locus in the neuron-specific medium neurofilament gene, a binding site for BRG1 in neurons and brain but not in T cells. The results are the average and standard deviation of three ChIP experiments. A) BRG1 binding. B) BAF180 binding. C) BAF250 binding.