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Table 3 The associations between individual IL-13 promoter variants and SMA

From: Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels

Genotypes Odds Ratio 95% CI P value
IL-13 -7402 T > G
TT, (n = 334) 1.000 - -
TG, (n = 49) 1.168 0.626-2.180 0.625
GG, (n = 4) 1.871 0.240-14.597 0.550
IL-13 -4729 G > A
GG, (n = 205) 1.000 - -
GA, (n = 131) 1.589 0.995-2.539 0.052
AA, (n = 51) 1.484 0.777-2.835 0.232
  1. Multivariate logistic regression analyses were used to determine the odds ratio (OR) and 95% Confidence Interval (CI), controlling for age, gender, G6PD deficiency, sickle-cell trait status and presence of bacterial infections [10, 13, 3638]. The homozygous wild-type genotypes were used as reference group for the regression analyses.