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Table 4 The distributions of IL-13 promoter haplotypes in the clinical groups

From: Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels

Haplotypes Non-SMA (Hb ≥ 6.0 g/dL) n (%) SMA (Hb < 6.0 g/dL) n (%) P value
-7402G/-4729G 1 28 (12.6) 25 (15.2) 0.472a
0 194 (87.4) 140 (84.8)
-7402 T/-4729A 1 94 (42.3) 87 (52.7) 0.043 a
0 128 (57.7) 78 (47.3)
-7402 T/-4729G 1 183 (82.4) 128 (77.6) 0.234a
  0 39 (17.6) 37 (22.4)  
  1. Haplotypes were constructed based on the IL-13 variants using the HPlus software. On the Table, 1 represents carriers of the haplotypes, while 0 represents non-carriers. Distributions of haplotypes compared between the SMA and non-SMA groups using aχ2 test.