BMC Immunology

Table 4 The distributions of IL-13 promoter haplotypes in the clinical groups

From: Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels

Haplotypes	Non-SMA (Hb ≥ 6.0 g/dL) n (%)		SMA (Hb < 6.0 g/dL) n (%)	P value
-7402G/-4729G	1	28 (12.6)	25 (15.2)	0.472^a
-7402G/-4729G	0	194 (87.4)	140 (84.8)	0.472^a
-7402 T/-4729A	1	94 (42.3)	87 (52.7)	0.043 ^a
-7402 T/-4729A	0	128 (57.7)	78 (47.3)	0.043 ^a
-7402 T/-4729G	1	183 (82.4)	128 (77.6)	0.234^a
	0	39 (17.6)	37 (22.4)

Haplotypes were constructed based on the IL-13 variants using the HPlus software. On the Table, 1 represents carriers of the haplotypes, while 0 represents non-carriers. Distributions of haplotypes compared between the SMA and non-SMA groups using ^aχ² test.

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