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Table 5 The associations between IL-13 promoter haplotypes and SMA

From: Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels

Haplotypes Odds Ratio 95% CI P value
-7402G/-4729G, (n = 53) 1.211 0.663-2.212 0.533
-7402 T/-4729A, (n = 181) 1.564 1.023-2.389 0.039
-7402 T/-4729G, (n = 311) 0.760 0.449-1.286 0.307
  1. Multivariate logistic regression analyses were used to determine the odds ratio (OR) and 95% CI, controlling for age, gender, G6PD deficiency, sickle-cell trait status and presence of bacterial infections [10, 13, 3638]. The haplotype non-carriers were used as reference groups for the analyses in the regression analyses.