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Figure 2 | BMC Immunology

Figure 2

From: Anti-tumor necrosis factor VNAR single domains reduce lethality and regulate underlying inflammatory response in a murine model of endotoxic shock

Figure 2

Production and expression of TNF, IL-6 and IL-10. Panels A, B, and C show levels of cytokines in serum of groups LD100, LD100 + VNAR or LD100 + F(ab)2 at different times; while panels D, E, and F show the expression in liver of the same cytokines at same groups and times; data represent mean ± standard error. The differences among groups were determined using a Kruskal-Wallis test and post hoc analysis using a Dunn’s multiple comparison test; differences were considered significant when *p < 0.05, **p < 0.01, ***p < 0.001. N = 10 animals for each group and time point.

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