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Figure 3 | BMC Immunology

Figure 3

From: Anti-tumor necrosis factor VNAR single domains reduce lethality and regulate underlying inflammatory response in a murine model of endotoxic shock

Figure 3

Production of NO 2 -and expression of iNOS. Panel A shows levels of NO2- in serum of groups LD100, LD100 + VNAR or LD100 + F(ab)2 at different times; panel B shows expression of iNOS in the same groups and times; data represent mean ± standard error. Differences among groups were determined using a Kruskal-Wallis test and post hoc using a Dunn’s multiple comparison test; differences were considered significant when *p < 0.05, **p < 0.01, **p < 0.001. N = 10 animals for each group and time point.

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