Skip to main content

Table 4 Allele frequencies of STAT6 single nucleotide polymorphisms in HCV-1 and HCV-2 infected patients receiving PEG-IFNα-RBV therapy with and without a SVR in a Chinese population in Taiwan

From: The impact of polymorphisms in STAT6 on treatment outcome in HCV infected Taiwanese Chinese

HCV-1

HCV-2

SNP ID

SVR (+)

SVR (−)

P

OR (95% CI)

SNP ID

SVR (+)

SVR (−)

P

OR (95% CI)

 

N (%)

N (%)

   

N (%)

N (%)

  

rs1059513

rs1059513

A allele

294 (90.2)

195 (95.6)

 

0.42 (0.20, 0.91)

A allele

333 (93.5)

32 (94.1)

 

0.90 (0.20, 4.01)

G allele

32 (9.8)

9 (4.4)

0.0235*

1

G allele

23 (6.5)

2 (5.9)

0.8954

1

rs703817 a

rs703817

A allele

80 (24.5)

63 (31.2)

 

0.72 (0.49, 1.06)

A allele

93 (26.1)

5 (14.7)

 

2.05 (0.77, 5.45)

G allele

246 (75.5)

139 (68.8)

0.0948

1

G allele

263 (73.9)

29 (85.3)

0.1425

1

rs324015 a

rs324015

A allele

145 (44.5)

89 (44.1)

 

1.02 (0.71, 1.45)

A allele

172 (48.3)

20 (58.8)

 

0.65 (0.32, 1.34)

G allele

181 (55.5)

113 (55.9)

0.9249

1

G allele

184 (51.7)

14 (41.2)

0.2416

1

rs3024974

rs3024974 b

C allele

258 (79.1)

161 (78.9)

 

1.01 (0.66, 1.56)

C allele

285 (80.5)

27 (79.4)

 

1.07 (0.45, 2.56)

T allele

68 (20.9)

43 (21.1)

0.9518

1

T allele

69 (19.5)

7 (20.6)

0.8777

1

  1. a Contains 1 missing data point in the SVR (−) group.
  2. b Contains 1 missing data point in the SVR (+) group.
  3. Abbreviations: SNP single nucleotide polymorphism, SVR sustained virological response, OR odds ratio, CI confidence interval.
  4. Allele frequencies were determined by χ2 test using 2 × 2 tables. Odds ratios and 95% CI per allele were estimated by unconditional logistic regression. P values less than 0.05 were considered statistically significant, and are denoted with an asterisk.