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Table 7 Predictive factors associated independently with the SVR to PEG-IFNα-RBV therapy in HCV-1 infected populations by multivariate logistic regression analysis

From: The impact of polymorphisms in STAT6 on treatment outcome in HCV infected Taiwanese Chinese

Parameter

P value

OR (95% CI)

Haplotype§ (GGGC/non-GGGC)

0.043*

2.32 (1.03, 5.23)

Age

0.012*

0.97 (0.94, 1.00)

BMI

0.060

0.92 (0.85, 1.00)

HCV-RNA levelδ (low/high)

0.050*

8.11 (0.98, 67.32)

  1. Abbreviation: CI confidence interval, BMI body mass index.
  2. § The order of the SNPs comprising the STAT6 haplotype was rs1059513, rs703817, rs324015, and rs3024974.
  3. δ Low HCV-RNA level: <100 KIU/ml by Amplicore-monitor assay. Odds ratios (OR) of having a SVR to PEG-IFNα-RBV therapy were calculated. P values less than 0.05 were considered statistically significant, and are denoted with an asterisk.