A comparison of sex-specific immune signatures in Gulf War illness and chronic fatigue syndrome

BMC Immunology

Table 3 Linear classification models separating healthy female subjects from female subjects with GWI or CFS

	Model	Stand. coeff.	Assigned HC	Assigned GWI or CFS	Total		Accuracy	NPV	PPV	Specificity	Sensitivity
Female GWI Subjects
GWI vs HC females at T0	NA					True HC female	NA	NA	NA	NA	NA
						True GWI female
GWI vs HC females at T1	Il-5 T1	1.20	8	1	9	True HC female	0.84	0.80	0.89	0.89	0.80
	Il-17 T1	−1.03	2	8	10	True GWI female
GWI vs HC females at T2	Il-23 T2	−1.00	8	1	9	True HC female	0.79	0.73	0.88	0.89	0.70
			3	7	10	True GWI female
GWI vs HC females at T0-T2	Il-23 T2	−1.00	8	1	9	True HC female	0.84	0.80	0.89	0.89	0.80
	Il-5 T1	0.99	2	8	10	True GWI female
Female CFS Subjects
CFS vs HC females at T0	Il-4 T0	−0.84	5	4	9	True HC female	0.74	0.83	0.69	0.56	0.90
	Il-17 T0	0.77	1	9	10	True CFS female
CFS vs HC females at T1	Il-2 T1	−1.00	4	5	9	True HC female	0.63	0.67	0.62	0.44	0.80
			2	8	10	True CFS female
CFS vs HC females at T2	Il-2 T2	−1.00	3	6	9	True HC female	0.68	1.00	0.63	0.33	1.00
			0	10	10	True CFS female
CFS vs HC females at T0-T2	Il-2 T1	−1.00	4	5	9	True HC female	0.68	0.80	0.64	0.44	0.90
			1	9	10	True CFS female
** All possible subsets
CFS vs HC females at T0-T2	IL-17_T1	1.00	8	1	9	True HC female	0.79	0.73	0.88	0.89	0.70
	IL-10_T2	−1.68	3	7	10	True CFS female

ISSN: 1471-2172