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Table 1 Characteristics of subjects

From: Local and systemic neutrophilic inflammation in patients with lung cancer and chronic obstructive pulmonary disease

Variable Lung cancer group Control group
Without COPD n = 139 With COPD n = 55 COPD n = 40 Healthy individuals n = 33
Gendera     
 Male 103 (74.1) 50 (90.9) 36 (90.0) 24 (72.7)
 Female 36 (25.9) 5 (9.1) 4 (10.0) 9 (27.3)
Age, mean ± SEM, years 63.1 ± 0.9 64.5 ± 1.2 65.4 ± 1.2 62.6 ± 0.9
BMI, mean ± SEM, kg/m2 27.3 ± 0.4 26.9 ± 0.5 28.4 ± 0.6 26.7 ± 0.6
Smoking historyaa     
 Never smoker 30 (21.6) 0 0 11 (33.3)
 Former smoker 27 (19.4) 7 (12.7) 19 (47.5) 10 (30.3)
 Current smoker 82 (59.0) 48 (87.3) 21 (52.5) 12 (36.4)
Smoking pack-years, median (range):     
 Former smoker 28.0 (10–54) 30.0 (15–40) 33.0 (13–57) 22.0 (11–44)
 Current smoker 38.0 (10–60) 40.0 (12–60) 39.5 (10–94) 32.0 (20–56)
FEV1, mean ± SEM, % pred 91.2 ± 1.7* 56.7 ± 1.6§ 55.7 ± 2.3§ 106.6 ± 3.0
FEV1/FVC ratio, mean ± SEM, % pred 96.6 ± 0.7* 70.6 ± 1.1§ 74.0 ± 1.8§ 104.8 ± 0.4
  1. FEV1 forced expiratory volume in one second, FVC forced vital capacity, BMI body mass index, COPD chronic obstructive pulmonary disease.
  2. *P < 0.05, when compared to lung cancer with COPD, COPD, and healthy individuals groups.
  3. §P < 0.05, when compared with healthy individuals.
  4. aχ2-10.61, P < 0.05.
  5. aaχ2-48.14, P < 0.001.