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Table 2 Distribution of genotype and allele frequencies of IL1A SNP

From: Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus

Gene

Different genetics models

 

IL1A

 

Controls

Cases

Multiplicative

Additive

Dominant

Recessive

SNP ID

Genotype

No (%)

No (%)

P value

OR

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

RS1304037

AA

161 (83.9)

130 (77.8)

0.262

1.32 (0.81-2.15)

  

0.147

1.48 (0.87-2.51)

0.386

0.38 (0.04-3.69)

AG

28 (14.6)

36 (21.6)

  

0.223

0.26 (0.03-2.63)

    

GG

3 (1.5)

1 (0.6)

  

0.432

0.41 (0.04-4.02)

    

rs16347

DEL/DEL

81 (42.2)

68 (40.7)

0.482

1.12 (0.82-1.51)

  

0.778

1.06 (0.70-1.62)

0.323

1.36 (0.74-2.48)

DEL/TGAA

88 (45.8)

73 (43.7)

  

0.343

1.36 (0.72-2.59)

    

TGAA/TGAA

23 (12.0)

26 (15.6)

  

0.367

1.35 (0.70-2.57)

    

rs17561

GG

166 (86.5)

121 (72.5)

0.003

2.08 (1.27-3.41)

  

0.001

2.43 (1.42-4.15)

0.646

0.54 (0.05-6.37)

GT

24 (12.5)

45 (26.9)

  

0.260

0.27 (0.02-3.10)

    

TT

2 (1.0)

1 (0.6)

  

0.758

0.69 (0.06-7.66)

    

rs2071373

CC

80 (41.7)

68 (40.7)

0.443

1.13 (0.83-1.53)

  

0.856

1.04 (0.68-1.59)

0.194

1.51 (0.81-2.84)

CT

92 (47.9)

74 (44.3)

  

0.191

1.55 (0.80-3.02)

    

TT

20 (10.4)

25 (15.0)

  

0.259

1.47 (0.75-2.88)

    
  1. CI, confidence interval; OR, odds ratio. The P values <0.05 were highlighted in boldface.
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BMC Immunology

ISSN: 1471-2172

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