Table 3 Distribution of genotype and allele frequencies of IL1B SNP
Gene | 4 statistical models | Â | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
IL1B | Â | Controls | Cases | Multiplicative | Additive | Dominant | Recessive | ||||
SNP ID | Genotype | No (%) | No (%) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) |
rs1143623 | GG | 57 (29.7) | 37 (22.2) | 0.106 | 1.27 (0.95-1.71) | Â | Â | 0.105 | 1.48 (0.92-2.40) | 0.318 | 1.28 (0.79-2.07) |
GC | 92 (47.9) | 85 (50.9) | Â | Â | 0.633 | 1.13 (0.68-1.89) | Â | Â | Â | Â | |
CC | 43 (22.4) | 45 (26.9) | Â | Â | 0.11 | 1.61 (0.90-2.90) | Â | Â | Â | Â | |
rs3917345 | DEL/DEL | 191 (99.5) | 166 (99.4) | 0.541 | 1.15 (0.07-18.47) |  |  | 0.541 | 1.15 (0.07-18.55) | — | — |
DEL/TGGT | 1 (0.5) | 1 (0.6) |  |  | — | — |  |  |  |  | |
TGGT/TGGT | 0 (0.0) | 0 (0.0) |  |  | — | — |  |  |  |  | |
rs1143627 | TT | 84 (43.8) | 47 (28.1) | 0.002 | 1.62 (1.20-2.18) | Â | Â | 0.002 | 1.99 (1.28-3.09) | 0.063 | 1.68 (0.97-2.91) |
TC | 81 (42.2) | 84 (50.3) | Â | Â | 0.399 | 1.29 (0.72-2.31) | Â | Â | Â | Â | |
CC | 27(14.1) | 36 (21.6) | Â | Â | 0.005 | 2.38 (1.29-4.40) | Â | Â | Â | Â | |