Figure 1
From: Anti-inflammatory effect of a retrovirus-derived immunosuppressive peptide in mouse models
Schematic representation of the retroviral envelope protein (not to scale). Top figure displays some of the functional elements in the transmembrane subunit. The fusion peptide (FP) and the Heptad Repeat I/II (HR) followed by the membrane transversing region (TM). The Immunosuppressive Domain (ISD) is located just N-terminal of the highly conserved CC-motif forming a vital disulphide bond. Stipulated lines indicate amino acid position in the alignment. Fr-MLV Friend Murine Leukemia Virus; FeLV Feline Leukemia Virus; GALV Gibbon Ape Leukemia Virus; MPMV Mason-Pfizer Monkey Virus; ALV Avian Leukosis Virus; HTLV Human T-lymphotropic Virus. GeneBank accession numbers indicated in parenthesis.