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Table 1 Intranasal challenge experiments in BALB/c mice using B. pertussis WHO reference strain 18323

From: A proteoliposome formulation derived from Bordetella pertussis induces protection in two murine challenge models

Treatments (s.c. immunization)

Bacteria recovered post challenge (Log CFU/g lung ± S.D.)

 

2 hrs

4th day

7th day

DTwP vaccine

7.85 ± 0.39

NR

NR

B. pertussis PL

6.68 ± 0.65

NR

NR

PBS

8.02 ± 0.2

6.85 ± 0.44

6.48 ± 0.11

  1. NR. Not recovered