Figure 1
From: Impact of endobronchial allergen provocation on macrophage phenotype in asthmatics
Kinetics of M2 polarization in mice after the induction of an acute allergic airway inflammation. Alveolar (AMΦ, open circles) and interstitial (IMΦ, closed circles) macrophages were isolated 1 day (24 h), 1 week (wk), 2 wk and 3 wk after ovalbumin aerosol provocation. A, Eosinophil numbers, IL-4 and IL-13 levels (n = 7). Data were analyzed with one way ANOVA. *** P < .001. B, Gene expression of M2 markers Arginase, Fizz1, and YM1 are presented as fold induction compared to PBS treated mice (each data point represents n = 5 pooled animals).