Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | Cluster 5 | ||
---|---|---|---|---|---|---|
n = 33 | n = 18 | n = 4 | n = 8 | n = 16 | ||
IgG | g/L | 4.37 (3.80, 5.32) | 5.73 (4.7, 6.3) | 4.68 (2.69, 5.29) | 1.44 (0.30, 2.71) | 3.69 (1.65, 4.22) |
IgA | g/L | 0.63 (0.14, 1.62) | 1.02 (0.07, 1.55) | 0.60 (0.04, 2.09) | 0.15 (0.01, 0.43) | 0.19 (0.05, 0.79) |
IgM | g/L | 0.55 (0.31, 1.09) | 0.48 (0.24, 0.78) | 0.54 (0.34, 0.62) | 0.16 (0.05, 0.42) | 0.27 (0.20, 0.47) |
B cells | ||||||
CD19+ | cells/mm3 | 157 (128, 244) | 128 (102, 211) | 49 (20, 87) | 122 (94, 176) | 51 (29, 119) |
CD27-IgD+ | % CD19+ | 68.85 (52.03, 74.47) | 68.89 (57.94, 77.24) | 49.52 (10.73, 80.43) | 90.89 (82.94, 93.31) | 84.03 (70.93, 90.82) |
CD27-IgD- | % CD19+ | 2.80 (2.18, 4.38) | 3.90 (2.24, 6.42) | 6.13 (2.64, 23.40) | 2.40 (1.67, 2.58) | 2.65 (1.72, 4.22) |
CD27 + IgD+ | % CD19+ | 15.01 (10.11, 23.19) | 10.53 (4.42, 13.73) | 5.67 (2.43, 8.57) | 3.57 (2.21, 7.20) | 4.92 (1.32, 7.92) |
CD27 + IgD- | % CD19+ | 14.39 (7.08, 20.05) | 13.93 (7.26, 24.33) | 7.77 (2.43, 19.38) | 2.55 (0.94, 3.91) | 2.97 (0.36, 6.66) |
T cells | ||||||
CD3+ | cells/mm3 | 1363 (1076, 1787) | 1045 (883, 1456) | 2756 (1472, 4183) | 831 (658, 1075) | 579 (407, 837) |
CD4+ | cells/mm3 | 835 (571, 1214) | 789 (573, 967) | 848 (609, 1227) | 382 (302, 565) | 308 (244, 565) |
CD8+ | cells/mm3 | 477 (358, 604) | 270 (159, 383) | 1621 (710, 2682) | 293 (196, 362) | 213 (141, 266) |
CD4+/CD8+ ratio | 1.89 (1.45, 2.42) | 2.77 (2.31, 4.08) | 0.60 (0.42, 1.06) | 1.26 (0.67, 2.65) | 1.89 (1.17, 2.61) | |
CD8+ T cells | ||||||
CD45RA + CCR7+ | % CD8+ | 19.05 (11.11, 34.59) | 28.47 (13.32, 43.67) | 1.52 (0.56, 2.75) | 4.91 (1.53, 53.19) | 35.56 (10.29, 53.19) |
CD45RA-CCR7+ | % CD8+ | 0.83 (0.46, 1.90) | 4.60 (1.96, 7.97) | 0.53 (0.21, 0.82) | 0.82 (0.30, 1.20) | 1.37 (0.85, 1.96) |
CD45RA-CCR7- | % CD8+ | 31.28 (24.26, 36.96) | 43.13 (32.60, 57.14) | 36.82 (16.56, 57.25) | 39.24 (30.69, 59.20) | 29.14 (17.47, 42.55) |
CD45RA + CCR7- | % CD8+ | 41.48 (32.61, 52.32) | 22.30 (16.87, 27.10) | 40.75 (13.96, 59.90) | 48.28 (30.47, 63.41) | 29.25 (18.76, 39.37) |
CD8 + CD57+ | % CD8+ | 17.52 (9.42, 30.97) | 7.38 (4.41, 15.97) | 27.36 (19.36, 47.30) | 39.61 (33.78, 51.16) | 13.51 (8.35, 23.44) |
Activated T cells | ||||||
CD3 + HLA-DR+ | % CD3+ | 12.04 (7.62, 16.95) | 9.87 (7.11, 12.83) | 52.00 (32.71, 59.56) | 46.56 (40.76, 57.25) | 13.65 (6.19, 20.33) |
CD4 + HLA-DR+ | % CD4+ | 5.88 (4.94, 9.17) | 6.75 (4.95, 9.13) | 48.30 (26.32, 56.25) | 43.87 (30.88, 49.95) | 11.54 (6.52, 18.33) |
CD8 + HLA-DR+ | % CD8+ | 25.48 (14.86, 31.93) | 19.73 (14.18, 26.44) | 53.48 (37.05, 65.52) | 62.14 (47.01, 76.39) | 15.12 (10.65, 28.64) |
Regulatory T cells | cells/mm3 | 54 (33, 76) | 41 (24, 82) | 18 (13, 22) | 19 (12, 24) | 15 (8, 18) |
NK cells | cells/mm3 | 143 (100, 214) | 174 (121, 230) | 268 (146, 388) | 75 (55, 103) | 41 (26, 70) |
Dendritic cells | ||||||
Myeloid | /ml | 11940 (8751, 17805) | 11422 (6616, 13457) | 9122 (5662, 29989) | 7795 (4086, 10548) | 5420 (4107, 9683) |
Plasmacytoid | /ml | 7217 (4801, 11084) | 6152 (3599, 9836) | 2771 (1766, 8490) | 3073 (1351, 3618) | 2766 (2194, 4255) |
Gammadelta cells | cells/mm3 | 44 (20, 74) | 27 (11, 54) | 396 (178, 579) | 19 (6, 92) | 16 (9, 26) |
Gammadelta 2 | % GD | 62.96 (40.85, 73.68) | 78.71 (75.00, 89.39) | 13.40 (8.77, 30.62) | 6.59 (4.09, 25.61) | 25.00 (12.41, 55.96) |