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Figure 1 | BMC Immunology

Figure 1

From: Streptococcus sanguinis-induced cytokine and matrix metalloproteinase-1 release from platelets

Figure 1

Streptococcus sanguinis -induced soluble molecule secretion from platelets. Platelets were stirred in with either S. sanguinis strain 2017–78 (n = 15), collagen (2 μg/ml; n = 5) or saline control (Unstimulated; n = 11). Release reactions were terminated and the levels of (A) sCD40L, (B) VEGF, (C) SDF-1, (D) MMP-1, (E) MMP-2 and (F) MMP-9 in the releasates determined by multi-plex luminex. Results are mean ± SEM of several individual experiments using the platelets from different donors and subsequently analyzed using the Mann–Whitney U-test (#P < 0.05 with respect to saline control; *P < 0.05 with respect to the saline control).

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