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Table 1 Characteristics and MBL genotypes of 72 patients with ASCT

From: Mannose-binding lectin gene variants and infections in patients receiving autologous stem cell transplantation

 

AA Patients (%) n = 53

AO/OO Patients (%) n = 19

P-value*

Gender

   

  Male

30 (56.6)

12 (63.2)

0.62

  Female

23 (43.4)

7 (36.8)

 

Mean age (SD), years

51.6 (13.9)

50.2 (14.8)

0.70

Underlying disease

  

0.78

  MM

14 (26.4)

6 (31.6)

 

  HD

8 (15.1)

5 (26.3)

 

  NHL

22 (41.5)

7 (36.8)

 

  AMN

7 (13.2)

1 (5.3)

 

  PL

1 (1.9)

0

 

  Amyloidosis

1 (1.9)

0

 

Active disease**

  

0.22

  YES

11 (20.8)

7 (36.8)

 

  NO

42 (79.2)

12 (63.2)

 
  1. *Two-tailed Chi-squared test/Fisher exact test for categorical variables or two-tailed t-test for continuous variables.
  2. **Active pre-transplant hematologic disease.
  3. MM: multiple myeloma, HD: Hodgkin disease, NHL: non Hodgkin lymphoma, AMN: acute myeloid neoplasia, PL: prolymphocytic leukemia, ME: multiple sclerosis.
  4. AA genotype: patients homozygous for wild-type structural allele (A).
  5. AO/OO genotype: patients heterozygous or homozygous for the B, C or D alleles.