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Figure 3 | BMC Immunology

Figure 3

From: IL-33 is negatively associated with the BMI and confers a protective lipid/metabolic profile in non-diabetic but not diabetic subjects

Figure 3

IL-33 is associated with favorable serum lipid profiles and HbA1c in non-diabetic subjects. (a) IL-33 is positively correlated with HDL-C (n = 31; Spearman r = 0.388, P = 0.03) but negatively correlated with total cholesterol (n = 31; Spearman r = -0.356, P = 0.049), LDL-C (n = 30; Spearman r = -0.44, P = 0.0158), and TGL (n = 31; Spearman r = -0.426, P = 0.0169) levels in non-diabetic subjects. (b) IL-33 is negatively correlated with cholesterol to HDL-C ratio (n = 31; Spearman r = -0.46, P = 0.009), LDL-C to HDL-C ratio (n = 31; Spearman r = -0.5, P = 0.004), TGL to HDL-C ratio (n = 31; Spearman r = -0.44, P = 0.013) and HbA1c (n = 31; Spearman r = -0.387, P = 0.03) in non-diabetic subjects. (c) IL-33 is negatively correlated with cholesterol to HDL-C ratio (n = 13; Spearman r = -0.54, P = 0.058), LDL-C to HDL-C ratio (n = 13; Spearman r = -0.59, P = 0.03) and HbA1c (n = 13; Spearman r = -0.61, P = 0.02), but positively correlated with HDL-C (n = 13; Spearman r = 0.59, P = 0.04), in non-diabetic obese subjects.

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