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Table 1 Summary of patient characteristics

From: Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults

Characteristics

N = 61

Age

18 (<1–65)*

Children ( <18 y )

29

Sex ( M/F )

38/23

Diagnosis:

 

Non-malignant

13

Acute myeloid leukemia/Acute lymphoid leukemia

12/13

Chronic lymphoid leukemia

4

Myelodysplastic syndrome

11

Other malignancies

8

Stage ( early/late )

16/32

Donor age

26 (0–62)

Donor sex ( M/F )

38/23

Donor

 

Sibling/HLA-identical, related

21

MUD

32

HLA-mismatched, unrelated

8

Conditioning

 

MAC/RIC

34/27

Chemo-based

38

TBI-based

23

ATG

47 (77%)

GVHD prophylaxis

 

CsA ± MTX

41

CsA + Prednisolon

3

Tacrolimus + Sirolimus

16

CsA + MTX + Cy

1

Stem cell source:

 

BM/PBSCs/CB

25/31/5

  1. *Median [4].
  2. Abbreviations: MUD matched unrelated donor, MAC myeloablative conditioning, RICreduced-intensity conditioning, TBI total body irradiation, ATG anti-thymocyte globulin, GVHD graft-versus-host disease, CsA cyclosporine, MTX methotrexate, Cy cyclophosphamide, BM bone marrow, PBSCs peripheral blood stem cells, CB cord blood.