Figure 8

In vitro effect of immunosuppressives on the percentage of CD14+CD163+ monocytes peripheral blood monocytes collected from a healthy donor were cultured in the presence of rATG, basiliximab and methylprednisolone. Membrane expression of CD163 on cultured monocytes was measured at following time points: 0, 1, 3, 6, 24, 48 and 72 h. Both the rATG (a) and methylprednisolone (b) upregulated the proportion of CD14+CD163+ monocytes while basiliximab (c) had no effect. Dynamics of the parameters was fitted by quadratic regression and the estimated coefficients were compared by z-statistcs.