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Figure 4 | BMC Immunology

Figure 4

From: Vitamin D receptor expression controls proliferation of naïve CD8+ T cells and development of CD8 mediated gastrointestinal inflammation

Figure 4

Proliferation of CD8+T cells in vivo . (A) Histograms showing BrdU incorporation in the MLN or IEL following transfer of sorted 106 WT or VDR KO CD8+ T cells into Rag KO recipients from 3 to 14 days post-transfer. Shaded histograms showed the BrdU isotype control staining, and open histograms were BrdU staining. (B) Different CD8+ subsets were evaluated for BrdU incorporation and graphed at day 3 and day 8 post-transfer. Naïve CD8+ T cells are CD62LhighCD44low, and activated CD8+ T cells are CD62LlowCD44high. Data is from n = 6-8 mice per group and the values represent the mean of two independent experiments ± SEM. ANOVA, *P < 0.05, **P < 0.01.

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