Skip to main content

Table 2 Effects of various inflammatory agents on the binding of CD11b antibody to human neutrophils.

From: Modulation of neutrophil function by the tripeptide feG

 

CD11b

CD16b

Stimulant

Control

Stimulant

Stimulant & feG1

Control

Stimulant

Stimulant & feG

PAF2

148.1 ± 12.83

291.6 ± 14.1#

242.1 ± 16.3*

357.4 ± 55.4

450.7 ± 62.5

291.9 ± 80.3*

IL-8

283.1 ± 36.0

455.9 ± 39.8#

459.5 ± 49.9

490.8 ± 49.6

551.6 ± 68.2

516.5 ± 59.2

LTB4

325.8 ± 72.8

367.4 ± 69.1

425.9 ± 74.4

555.6 ± 117.3

588.6 ± 117.3

565.3 ± 94.6

C5a

227.4 ± 35.4

415.1 ± 36.8#

445.1 ± 29.9

433.7 ± 55.2

447.1 ± 41.5

419.3 ± 53.4

TNF

260.2 ± 28.3

270.3 ± 28.6

297.5 ± 33.7

528.2 ± 67.7

467.7 ± 44.3

490.0 ± 50.7

  1. 1Concentration of feG = 10-11M. 2Concentrations of stimulants: PAF = 10-9M; IL-8 = 10-9M; LTB4 = 10-9M; C5a = 1%; TNF = 5ng/ml. 3 Values expressed as mean ± SEM for n = 3–11. Significance (P < 0.05): # greater than Control; * less than Stimulant alone.