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Table 3 feG inhibition of antibody binding to CD11b and CD16b requires free N-terminal amide and C-terminal carboxyl groups.

From: Modulation of neutrophil function by the tripeptide feG

Condition

CD11b

CD16b

Basal

220.2 ± 17.72

401.1 ± 55.2

PAF (10-9M)

381.9 ± 23.0

479.2 ± 62.1

PAF & feG1

278.1 ± 23.7*

291.9 ± 80.3*

PAF & feG(NH2)

381.5 ± 54.7

446.9 ± 69.5

PAF & AcfeG

350.1 ± 61.2

425.4 ± 57.7

PAF & feA

384.8 ± 33.7

458.3 ± 36.6

  1. 1Concentrations of peptides = 10-11M. 2 Values of Mean Fluorescence Intensity expressed as mean ± SEM for n = 4–7. Significance: * less than PAF alone.
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BMC Immunology

ISSN: 1471-2172

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