Figure 1

Integrin β7 expression on blood T helper cells and on purified β7^- and β7⁺ memory T helper cell subsets. Dot density plots depicting expression of the naïve cell marker CD45RA and integrin β7 on CD4⁺ blood T cells (A) and on purified β7⁺ (B) and β7^- (C) memory cells in arbitrary fluorescence units. Sorted populations were ~99% pure. Quadrant markers indicate settings used to sort populations based on CD45RA and β7 expression. Colors indicate the relative frequency of cells (from lowest to highest density: green, purple, light blue, orange, dark blue, and yellow).