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Table 1 Putative P Nucleotides in a dataset of 294 human IgM sequences

From: Exonuclease activity and P nucleotide addition in the generation of the expressed immunoglobulin repertoire

Gene Segment

Putative P Sequence

Observed

Total Junctions

p-value1

IGHV

C

10

111

0.99

 

T

25

111

0.023

 

CC

2

105

0.99

 

TC

10

105

0.049

 

TG

2

105

0.98

 

TCT

3

100

0.045

 

TGT

1

100

0.55

 

TCTC

1

86

0.21

IGHD 5'

A

1

37

0.99

 

C

5

37

0.99

 

AC

1

36

0.86

 

CA

1

36

0.86

 

CC

2

36

0.96

 

CCC

1

33

0.77

IGHD 3'

G

11

40

0.88

 

GT

2

36

0.57

 

TC

1

36

0.86

 

GTT

3

33

0.0022

IGHJ

T

11

42

0.042

 

GT

3

34

0.26

 

AGC

1

32

0.45

 

ACT

2

32

0.026

  1. 1 α equal to 0.003
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BMC Immunology

ISSN: 1471-2172

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