Skip to main content

Table 2 Grouping of IGHJ genes by relative location of W and S motifs

From: Exonuclease activity and P nucleotide addition in the generation of the expressed immunoglobulin repertoire

J Gene Sequence1 Group
IGHJ1*01 GC TGAATACTTCC AG 5' S only
IGHJ2*01 TGCTACTGG TACTTG 5' S only
IGHJ3*01 TGATGC TTTT GATGT 5' S then W
IGHJ3*02 ATGC TTTT GATAT CT 5' S then W
IGHJ4*01 ACTACTTT GACTACT 5' W only
IGHJ4*02 ACTACTTT GACTACT 5' W only
IGHJ4*03 GC TACTTT GACTACT 5' S then W
IGHJ5*01 ACAACTGG TTCG ACT 5' S only
IGHJ5*02 ACAACTGG TTCG ACC 5' S only
IGHJ6*01 ATTA CTACTACTACT 5' W only
IGHJ6*02 ATTA CTACTACTACT 5' W only
IGHJ6*03 ATTA CTACTACTACT 5' W only
  1. 1W motifs shown underlined, S motifs shown in italics