Figure 1

Effect of adrenalectomy and restoration of various concentrations of corticosterone on the number of nucleated cells in the thymus 24 hours after implantation of corticosterone pellets Treatment groups were: Naive, untreated; ADX-N, adrenalectomized naive; ADX-P, adrenalectomized with placebo pellet implanted; other groups, adrenalectomized with corticosterone pellets of the indicated size implanted. The thymus was evaluated 24 hours after pellet implantation (~3–4 weeks after ADX). Group size was 5–12. Values shown are mean ± S.E. obtained by normalizing groups to the mean value for the Naive group (defined as 100%). Results shown are pooled from two independent experiments, and groups significantly different from the naive group (by ANOVA followed by Dunnett's test) are shown by * (p < 0.05) or ** (p < 0.01).