Skip to main content
Figure 8 | BMC Immunology

Figure 8

From: Thymus-derived glucocorticoids are insufficient for normal thymus homeostasis in the adult mouse

Figure 8

Effect of sub-physiological and stress-inducible concentrations of corticosterone on immature single positive (CD8+) thymocytes The histograms at the top of this figure illustrate the region containing cells that express low levels of CD3 (the larger purple peak on the histogram to the left, in which the isotope control is indicated by a green line), and the subsequent analysis of those cells for CD4 and CD8. The cells in the lower right quadrant (outlined with bold lines) are CD3lowCD8+, immature single positive cells. The values shown in the graphs are means ± SE for groups of 5 mice representing either the percentage of immature single positive cells in the thymus or the total number of these cells in the thymus (obtained by multiplying the percentage by the total thymus cell number for each mouse). Groups significantly different from the naive group (by ANOVA followed by Dunnett's test) are shown by ** (p < 0.01).

Back to article page