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Figure 5 | BMC Immunology

Figure 5

From: Fully automated synthesis of (phospho)peptide arrays in microtiter plate wells provides efficient access to protein tyrosine kinase characterization

Figure 5

Pattern of recognition of arrayed EGFR peptides by autophosphorylation site antibody (9H2) Tyrosine sequence positions correspond to human EGF receptor residue positions (Swissprot P0053, leader sequence removed). Amino acids are color coded for acidic, basic, hydrophilic, and hydrophobic as red, blue, green and brown. *. For (phospho)peptide array compositions and quantitative results [see Additional file 1]. Footnotes: 1. autophosphorylation site [26-28], 2. PLC-gamma SH2 domain binding[29], 3. GRB2/SH2 domain binding [30], 4. Shc, SHP1, PLC-gamma SH2 domain binding [31, 32], 5. Src phosphorylation site [33-35],6. AP2 [36, 37], 7. Cbl, SH2 domain binding [38-40], 8. Shc SH2 domain binding [31, 32, 41].

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BMC Immunology

ISSN: 1471-2172

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