Figure 2

a)Withdrawal latencies measured 3 hours after intraplantar carrageenan injection (basal measurement = time 0) and at different hours following oATP (100 ( μM in 0.15 ml saline, continuous line) or 0.9% saline (0.15 ml, hatched line) local intraplantar injection (circle). Mean ± SEM of 7 rats. * p < 0.05 compared to saline at the same time. b) Withdrawal latencies measured 3 hours after intraplantar carrageenan injection (basal measurement = time 0) and at different hours following oATP (100 μM in 0.15 ml saline, continuous line) or saline (0.15 ml, hatched line) oral administration (square). Mean ± SEM of 7 rats. * p < 0.05 compared to saline at the same time. c) Withdrawal latencies measured as previously (3 hours after local carrageenan injection = time 0) and at different hours of oATP (100 μM in 0.15 ml saline, continuous line) or saline (0.15 ml, hatched line) intravenous administration (triangle). Mean ± SEM of 7 rats. * p < 0.05 compared to saline at the same time.