Confocal microscopy on rat paws. The sections are doubly labeled with anti- IP-10 and IL-8 mAbs revealed by FITC- (green) or TRITC- (red) conjugated secondary Abs respectively. Merged Free Projection Max of images seriesshows cytokine expression after saline (a), carrageenan (b), carrageenan+oATP local treatment (c), carrageenan+oATP intravenous treatment (d), local oATP treatment (e), intravenous oATPtreatment (f). Nuclei are stained with DAPI (blue) (original magnification 400x). Notice thepresence of activated cells in the derma in b and f, the endoluminal signal in dermal small vessels(a, c, e) and the absence of cytokine labeling in d (original magnification 400x).