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Table 3 Genes involved in homeostasis and cell growth, which were found to be significantly up-regulated in PBMCs of SARS patients. Level of expression is expressed in Fold change (average of fold changes of ten patients, S1-S10) as compared to that of control samples from normal human subjects (C1-C4).

From: Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome

Gen Bank ID

Description

Gene name

Fold change (S1-S10)

BC005248.1

Eukaryotic translation initiation factor 1A

EIF1AY

44.79

NM_001008.1

Ribosomal protein S4, Y-linked

RPS4Y

20.75

NM_001062.1

transcobalamin I (vitamin B12 binding protein, R binder family)

TCN1

16.88

NM_002357.1

MAX dimerization protein

MAD

11.88

NM_012387.1

Peptidyl arginine deiminase, type V

PADI4

9.12

NM_000184.1

Hemoglobin, gamma G

HBG2

8.7

NM_000559.1

Hemoglobin, gamma A

HBG1

8.1

NM_004653.1

SMC (mouse) homolog, Y chromosome

SMCY

7.07

NM_002934.1

Ribonuclease, RNase A family, 2

RNASE2

5.99

M60721.1

Homeo box 1

HLX1

5.85

NM_005178.1

B-cell CLLlymphoma 3

BCL3

5.11

NM_001964.1

Early growth response 1

EGR1

4.9

NM_006931.1

Solute carrier family 2, member 3

SLC2A3

4.89

NM_002863.1

Phosphorylase, glycogen

PYGL

4.89

NM_021122.2

Fatty-acid-Coenzyme A ligase, long-chain 2

FACL2

4.87

L13974.1

Nuclear factor (erythroid-derived) 2

NFE2

4.77

AI313324

H2A histone family, member O

HIST2H2AA

4.48

BC002649.1

H1 histone family, member 2

HIST1H1C

4.44

AF073310.1

insulin receptor substrate-2

IRS2

4.43

NM_005330.2

hemoglobin, epsilon 1

HBE1

3.97

AF073890.1

Cathepsin X precursor

CTSZ

3.69

AB002559.1

syntaxin binding protein 2

STXBP2

3.69

NM_017445.1

H2B histone family, member S

HIST1H2BK

3.64

NM_003118.1

Secreted protein, acidic, cysteine-rich (osteonectin)

SPARC

3.62

AL353759

Two genes for novel histone 1

HIST1H2AC

3.54

NM_003681.1

Pyridoxal (pyridoxine, vitamin B6) kinase

PDXK

3.54

BC001886.1

Ribonucleotide reductase M2 polypeptide

RRM2

3.53

AI082078

Actinin, alpha1

ACTN1

3.42

AF087942.1

Glycogenin-1L

GYG

3.39

AL538601

Sjogren syndrome antigen A2

SSA2

3.36

NM_001805.1

CCAATenhancer binding protein

CEBPE

3.26

NM_003528.1

H2B histone family, member Q

HIST2H2BE

3.13

BC001906.1

Similar to metaxin 1

MTX1

3.11

NM_006755.1

Transaldolase 1

TALDO1

3.07

BC000893.1

Histone family, member A

HIST1H2BK

3.06

AL161952.1

Glutamate-ammonia ligase

GLUL

2.99

BC002842.1

H2B histone family, member B

HIST1H2BD

2.78

NM_004219.2

Pituitary tumor-transforming 1

PTTG1

2.75

NM_012228.1

Pilin-like transcription factor

PILB

2.73

L12711.1

Transketolase

TKT

2.68

BE561479

Glyceraldehyde-3-phosphate dehydrogenase

GAPD

2.61

NM_012331.2

Methionine sulfoxide reductase A

MSRA

2.6

M33197

Glyceraldehyde-3-phosphate dehydrogenase

GAPD

2.59

NM_005195.1

CCAAT enhancer binding protein

CEBPD

2.57

NM_018840.1

Putative Rab5-interacting protein

C20orf24

2.45

AA314406

Thyroid Hormone Receptor Associated protein

TRAP95

2.44

NM_004832.1

Glutathione-S-transferase like; glutathione transferase omega

GSTTLp28

2.42

NM_013272.2

Solute carrier family 21 (organic anion transporter)

SLC21A11

2.42