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Figure 2 | BMC Immunology

Figure 2

From: Reciprocal role of cyclins and cyclin kinase inhibitor p21WAF1/CIP1 on lymphocyte proliferation, allo-immune activation and inflammation

Figure 2

In vitro and in vivo mRNA expression of Cyclins relates to alloimmune activation: A: Cyclins; D3, E and G and β-actin mRNA expression in lymphocytes isolated from spleens of rat heart transplant recipients. Untreated (lanes 4,5), CsA treated (lanes 1,2,3). B: Mean ± SEM of the ratio cyclins with β-actin, p values are calculated between densitometric numbers of untreated and CsA treated transplant recipient. C: Cyclin D3 and pro-inflammatory cytokines mRNA expression in lymphocyte from MLR assay using stimulants from donor strain with responders from donor strain (Control) untreated rejecting transplant recipients (A) and CsA treated non rejecting transplant recipients (B). The p values represent the statistical significance between ratio of densitometric numbers for each gene with β-actin from untreated (Group A) vs CsA (Group B) treated transplant recipients.

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BMC Immunology

ISSN: 1471-2172

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