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Figure 3 | BMC Immunology

Figure 3

From: Reciprocal role of cyclins and cyclin kinase inhibitor p21WAF1/CIP1 on lymphocyte proliferation, allo-immune activation and inflammation

Figure 3

Over expression of p21WAF1/CIP1 inhibits proliferation and IL-2 mRNA expression in Jurkat T cells: A: A comparison of the proliferation of Jurkat T cells with and without p21 overexpression. B. Il-2 mRNA expression in PHA activated normal and p21 over-expressing Jurkat T cells. An identical expression of house keeping gene β-actin is also shown. C: p21 protein expression in four different clones of p21 overexpressing Jurkat T cells, Untreated (lane 1), p21 overexpressing (lane 2–5) and transfected with empty vector DNA (lane 6).

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