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Figure 10 | BMC Immunology

Figure 10

From: BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1

Figure 10

Anti-IgM rapidly upregulates BMP-6 mRNA expression in human B-cells. CD19-positive B cells were cultured in X-vivo 15 over night and stimulated with anti-IgM for the indicated time periods, before total RNA was extracted. The expression of BMP-6 mRNA by realtime RT-PCR; values are normalised to the expression level of PGK1 mRNA and expressed as relative quantification (2-average ΔΔCT – relative to BMP-6 expression in the cell-line Ramos. One representative of five independent experiments is shown.

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