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Table 1 Expression of trafficking determinants on CD4+ memory1 T cells in blood and CSF

From: Human cerebrospinal fluid contains CD4+ memory T cells expressing gut- or skin-specific trafficking determinants: relevance for immunotherapy

   CLA Integrin α4β7 CCR4 CCR9
   Blood CSF Blood CSF Blood CSF Blood CSF
NIND Mean 14.2 11.5 33.0 17.9 59.8 41.7 8.0 5.1
  SD 6.1 4.3 5.9 3.0 10.8 8.2 2.8 4.3
  n 10 10 4 4 5 5 8 8
MS Mean n.d. n.d. n.d. n.d. 69.6 48.4 n.d. n.d.
  SD      11.5 15.3   
  n      6 6   
  1. 1CD45RO+ or CD45RA- depending on staining protocol
  2. NIND = non-inflammatory neurological diseases; MS = multiple sclerosis; CLA = cutaneous leukocyte antigen