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Table 1 Expression of trafficking determinants on CD4+ memory1 T cells in blood and CSF

From: Human cerebrospinal fluid contains CD4+ memory T cells expressing gut- or skin-specific trafficking determinants: relevance for immunotherapy

  

CLA

Integrin α4β7

CCR4

CCR9

  

Blood

CSF

Blood

CSF

Blood

CSF

Blood

CSF

NIND

Mean

14.2

11.5

33.0

17.9

59.8

41.7

8.0

5.1

 

SD

6.1

4.3

5.9

3.0

10.8

8.2

2.8

4.3

 

n

10

10

4

4

5

5

8

8

MS

Mean

n.d.

n.d.

n.d.

n.d.

69.6

48.4

n.d.

n.d.

 

SD

    

11.5

15.3

  
 

n

    

6

6

  
  1. 1CD45RO+ or CD45RA- depending on staining protocol
  2. NIND = non-inflammatory neurological diseases; MS = multiple sclerosis; CLA = cutaneous leukocyte antigen