Figure 7
From: Sexual dimorphism in immune response genes as a function of puberty
Differences in serum IgG2a but not IgG2b levels are abolished in B6 IFN-gamma knockout mice (B6 GKO). Serum samples from 16- to 20-week-old male and female (4–6 mice/sex) B6 and B6 GKO mice were assayed by ELISA. Graphs represent mean absorbance at 405 nm ± SE. Significant differences for B6 IgG2a (p = 0.005), B6 IgG2b (p = 0.003) and B6 GKO IgG2b (0.001) between post-pubertal male (blue bar) and female (checker red bar) mice are shown with asterisks.