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Table 3 Summary of observed HLA associations of commonly recognized peptides and previously defined eptiopes contained within them.

From: CTL epitope distribution patterns in the Gag and Nef proteins of HIV-1 from subtype A infected subjects in Kenya: Use of multiple peptide sets increases the detectable breadth of the CTL response

Peptide set (protein)

Sequence

Number of responders

HLA allele in common

Previously defined epitope

A-Con1/C-Iso2 (Gag)

SLYNTVATLYC

5

A*0201

SLYNTVATL

A-Iso/D-Iso (Gag)

SLFNTIATL(Y/W)C

3

  

A-Con (Gag)

QSLSPRTLNAW

3

B*5703

LSPRTLNAW

A-Con/C-Iso/D-Iso (Gag)

EKAFSPEVIPMFSAL

5

B*5701/03

KAFSPEVIPMF

A-Iso (Gag)

EKGFNPEVIPMFSAL

3

  

A-Con/A-Iso (Gag)

EGATPQDLNMMLNIV

4

B*4202

TPQDLNMML

C-Iso/D-Iso (Gag)

EGATPQDLNTMLNTV

1

  

A-Con (Gag)

FRDYVDRFFKTLRAE

7

C W *0304

YVDRFFKTL

A-Con (Gag)

MKDCTERQANFLGKI

2

A*0101/03

ND3

A-Iso (Nef)

AVTSSNVNHPS

3

A*6802

ND3

A-Iso (Nef)

FPVRPQVPLRPMTYK

4

B*4201/02

VPLRPMTY

A-Iso (Nef)

FPVRPQVPLRPMTYK

2

B*5301

(B*3501)

A-Iso (Nef)

KKRQEILDLWVYHTQ

5

C W *0701

KRQEILDLWVY

A-Iso (Nef)

GIRYPLTFGWCFKLV

3

B*5301

YPLTFGWCY

  1. 1Con = Consensus peptide set
  2. 2Iso = Isolate peptide set
  3. 3ND = Not defined previously