Skip to main content

Table 1 Genes responsive to LPS that are known NF-κB targets or that have putative sites κB sites

From: Transcriptional profiling of the LPS induced NF-κB response in macrophages

Accession no Symbol Gene Name Reference
Chemokines and receptors
[genebank:NM_002983] CCL3 Chemokine, CC motif, Ligand 3 π [25]
[genebank:NM_002984] CCL4 Chemokine, CC motif, ligand 4 π [25]
[genebank:NM_005408] CCL13 Chemokine, CC motif, ligand 13 [68]
[genebank:NM_032964] CCL15 Chemokine, CC motif, ligand 15 [69]
[genebank:NM_006274] CCL19 Chemokine, CC motif, ligand 19 -1748*
[genebank:NM_002990] CCL22 Chemokine, CC motif, ligand 22 π [70]
[genebank:NM_001511] CXCL1 Chemokine CC motif, Ligand 1 π [25]
[genebank:NM_002089] CXCL2 Chemokine, CXC motif, ligand 2 π [25]
[genebank:NM_000584] CXCL8 Chemokine, CXC motif, ligand 8 π [25]
[genebank:NM_001565] CXCL10 Chemokine, CXC motif, ligand 10 [25]
[genebank:NM_005408] CXCL13 Chemokine, CXC motif, ligand 13 -1593*
[genebank:U28934] CCR2 Chemokine, CC motif, receptor 2 -1543*
[genebank:NM_003467] CXCR4 Chemokine, CXC motif, receptor 4 π [71]
Cytokines and Receptors
[genebank:NM_000594] TNF-α Tumour Necrosis Factor α π [25]
[genebank:NM_000576] IL1-β Interleukin 1 B π [25]
[genebank:NM_000577] IL1-RN Interleukin 1 receptor antagonist π [25]
[genebank:NM_005746] PBEF Pre B cell colony stimulating factor 1 π -533*, -479*
[genebank:NM_001250] TNFRSF5 TNF receptor superfamily, member 5 [72]
[genebank:NM_001561] TNFRSF9 TNF receptor superfamily member 9 [73]
[genebank:NM_005534] IFNGR2 Interferon, gamma receptor 2 -317, -220*, -144, -134*
Stress
[genebank:NM_000636] SOD2 Superoxide dismutase 2 πp [25]
[genebank:NM_000963] COX2 Cycloxygenase 2 π [25]
[genebank:NM_006427] TXNIP Thioredoxin interacting protein π -618
Apoptosis
[genebank:NM_015675] GADD45 β Growth arrest and DNA damage inducible gene GADD45, B π [74]
[genebank:NM_005879] TRIP Traf interacting protein -1736
[genebank:NM_006290] TNFAIP3 Tumour Necrosis factor α induced protein 3 π [25]
[genebank:NM_001165] cIAP2 Cellular inhibitor of apoptosis 2 π [75]
Transcription
[genebank:NM_020529] IκB-α Inhibitor of κlight chain gene enhancer in B cells; α π [25]
[genebank:NM_003998] NFκB1 Nuclear factor of κB, subunit 1 π [25]
[genebank:NM_002908] C-REL V-rel avain reticuloendotheliosis viral oncogene homolog; rel π [25]
[genebank:NM_005375] C-MYB V-MYB avian myeloblastosis viral oncogene homolog π [25]
[genebank:NM_004364] CEBPα CAAT/enhancer binding protein α [25]
[genebank:U96131] TRIP13 Thyroid hormone interactor 13 -1611, -1601*, -1600* -1464*
[genebank:NM_002129] HMGB2 High mobility group box 2 -1531, -1520, -1087
Cell Cycle/Differentiation
[genebank:NM_006763] BTG2 B-cell translocation gene 2 π [76]
[genebank:NM_002166] ID2 Inhibitor of DNA binding 2 π -571*, -174
[genebank:X54941] CKS1B CDC28 protein kinase 1B -1416, -1406* -717, -647, -637*, -646 -636*
[genebank:NM_004701] CCNB2 Cyclin B2 -1387
Growth
[genebank:NM_000598] IGFBP3 Insulin-like growth-factor binding protein 3 π -1729
Miscellaneous
[genebank:NM_000674] ADORA1 Adenosine A1 receptor [25]
[genebank:NM_000201] ICAM1 Intracellular adhesion molecule 1 π [25]
[genebank:NM_002421] MMP1 Matrix metalloproteinase 1 [25]
[genebank:X13895] SAA3P Serum amyloid A3 pseudogene -1790*
[genebank:NM_002291] LAMβ1 Laminin, β 1 -263, -253
[genebank:NM_004119] FLT3 FMS related tyrosine kinase 3 -295, -285*
[genebank:NM_001365] DLG4 Discs, large homolog 4 -1425, -1415*, -544*
[genebank:M22001] F13A1 Coagulation factor X111, A1 polypeptide -404, -72*
  1. LPS responsive genes that have been shown to be NF-κB targets (Reference is indicated) or contain putative κB sites. The position of the site in relation to the initiator ATG is indicated and * indicates the site is found on the reverse strand. π indicates genes validated using real time PCR.