Figure 3

Massive vacuole formation follows Cn extrusion by macrophages. Macrophage extrusion of Cn cells was followed by the formation of a massive vacuole ranging up to approximately 15 μM in size. This formation was not observed in bead infected or uninfected macrophages. The thin arrow points to the nascent vacuole which progressively grows over time to a large vacuole, as indicated by the thick arrow. Images were collected at 10×.