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Table 2 Transcriptional Factors altered by PAR-AP stimulation of the mouse bladder mucosa as detected by Protein/DNA combo array.

From: Transcription factor network downstream of protease activated receptors (PARs) modulating mouse bladder inflammation

Upregulated

 

AP-1

Fos, FosB, Fra1, Fra2, Jun, JunB [82]

AP-2

Activator protein 2 [83]

Brn-3

POU4F1: POU domain, class 4, transcription factor 1 [84]

GAS/ISRE

Gamma-interferon activation site [85]

GATA-3

GATA binding protein3 (globin transcription factor 3) [86]

HNF-4

Hepatocyte nuclear factor 4 [87]

HOX4C

homeo box4C [88]

Oct-1

POU2F1: POU domain, class 2, transcription factor 1 [89]

p53

TP53: tumor protein p53 [90]

PBX1

pre-B-cell leukemia transcription factor 1 [91]

PTF1

pancreas specific transcription factor [92]

RORE

RAR-related orphan receptor [93]

Tax/CREB

TAX & CREB complex-responsive protein [94]

TFEB

TFEB is a the b-HLH-LZ closely related to TFE3 [38]

Thy-1 BP

Thy-1binding protein [38]

Down Regulated

 

AIC, CBF

Apolipoprotein AI (ApoAI) promoter c region, CCAAT-binding factor ([95]

ARP

COUP-beta; apolipoprotein AI; NR2F2 ([95]

ATF/CRE

Activating transcription factor [96]

CREB2

cyclic AMP response element binding protein 2 [97]

Fra-1/JUN

Fos-related antigen [98]

Freac-7

Forkhead box L1 [99]

Gfi-1

Growth factor independent 1 [100]

HFH-2

Forkhead box D3 [101]

HNF-1A

Hepatocyte nuclear factor 1 [102]

HOXD9

HOXD9,10 [88]

HSE

Heat shock transcription factor [103]

kBF-A

kappa immunoglobulin enhancer binding protein [104]

Lactoferrin BP

Lactoferrin enhancer binding region for estrogen receptor [105]

LF-A2

Liver-specific transcription factor [106]

LXRE1

Nuclear receptor subfamily 1, group H, member 2 [107]

MTF

MRE-binding transcription factor-1 [108]

NF-1

CTF; NF-I; TGGCA-binding protein [109]

Pax2

Pax-2 DNA-binding transcription factor [110]

Pax5

Pax-5 DNA-binding transcription factor [111]

Snail

Zinc-finger transcription factor Snail [112]

T3R

c-ErbA; thyroid hormone receptor [113]

TEF1

TEF 1 box [114]

WAPBP

Whey acidic protein binding protein [115]