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Figure 3 | BMC Immunology

Figure 3

From: Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists

Figure 3

Cytokines secreted by flow purified pDC 4 hr post-stimulation with TLR7 agonists. Cell culture supernatants collected after stimulation were evaluated for cytokine protein expression using a Luminex 25-Plex assay. (A) Secreted TNFα, IL8, IFNα, MIP-1α, MIP-1β and IL6. (B) secreted IL1β, IL2R, IL12P70, Rantes, GM-CSF, MCP-1, and IP-10. Dotted bars, vehicle stimulated samples; hatched bars, 3M-852A-stimulated samples and solid bars, 3M-011-stimulated samples. The results are expressed as mean + SD, n = 2 donors.

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