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Figure 2 | BMC Immunology

Figure 2

From: Use of molecular modeling and site-directed mutagenesis to define the structural basis for the immune response to carbohydrate xenoantigens

Figure 2

The nucleotide and animo acid sequence of light chain genes encoding xenoantibodies induced in non-human primates. (A.) The nucleotide sequence of genes encoding the light chain of xenoantibodies are most similar to the human HSIGDPK5 and HSIGKV134 germline genes. The sequences shown here are aligned with the human HSIGDPK5 germline gene as well as to the closest germline progenitor identified in non-human primates, IGKVIz. The sequence of the genes encoding the light chain of xenoantibodies at day 21 is compared with that at day 0. Clone numbers are indicated in parenthesis. (B.) The amino acid translation of these sequences is shown.

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BMC Immunology

ISSN: 1471-2172

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