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Figure 3 | BMC Immunology

Figure 3

From: Use of molecular modeling and site-directed mutagenesis to define the structural basis for the immune response to carbohydrate xenoantigens

Figure 3

The sequence of the light chain genes encoding xenoantibodies in non-human primates that are most similar to the human germline gene HSIGKV134. (A.) The nucleotide sequence of genes encoding the light chain of xenoantibodies aligned with the human germline gene HSIGKV134 and the closest non-human primate germline gene, IGKVIf, is shown. The sequences of the genes encoding xenoantibody light chains at days 0 and 21 are compared. Clone numbers are indicated in parenthesis.(B.) The amino acid sequence of genes encoding the light chain of xenoantibodies.

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